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Cimetidine (Tagamet) increases blood levels of Glucophage affecting its metabolism. Glucophage is not compatible with alcohol. Concomitant administration with indirect anticoagulants and Cimetidine should be done with cautiousness. Glucophage enhances metabolism of Furosemide. Derivatives of sulfonylurea, insulin, acarbose, inhibitors of MAO, oxytetracycline, cyclophosphamide and salicylates increase the effects of Glucophage. Decrease of hypoglycemic effect of Glucophage is caused by co-administration with thyroid medicines, birth control pills and other hormones, Epinephrine, Glucagon, thiazide diuretics, nicotinic acid derivates.
Storage
This medication is able to cause a life threatening condition in some people which is characterized by weakness, increasing sleepiness, slow heartbeat, cold feeling, muscle pain, abdominal pain, shortness of breath, feeling light-headed, and fainting. It is called lactic acidosis. If you experience such symptoms get immediate medical attention. Also be attentive to symptoms of low blood sugar which include hunger, confusion, irritability, drowsiness, headache, weakness, fast heartbeat, tremors, sweating, seizure and have a source of sugar at hand always. Avoid drinking alcohol.
The following side effects are most common and be rather severe to stop taking of the medication: swelling or rapid weight gain, nausea, vomiting, gas, bloating, diarrhea and loss of appetite. In case of lactic acidosis also get emergency medical help: weakness, increasing drowsiness, slow heartbeat, cold feeling, shortness of breath, abdominal pain, muscle pain, lightheadedness, and fainting. Allergic reaction is also possible: hives, swelling, rash.
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Drug interaction
Overdose
Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.
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This medication is able to cause a life threatening condition in some people which is characterized by weakness, increasing sleepiness, slow heartbeat, cold feeling, muscle pain, abdominal pain, shortness of breath, feeling light-headed, and fainting. It is called lactic acidosis. If you experience such symptoms get immediate medical attention. Also be attentive to symptoms of low blood sugar which include hunger, confusion, irritability, drowsiness, headache, weakness, fast heartbeat, tremors, sweating, seizure and have a source of sugar at hand always. Avoid drinking alcohol.
Missed dose
Common use
Symptoms of Glucophage overdose are ones of low blood sugar: hunger, confusion, irritability, drowsiness, headache, weakness,, tremors, sweating, fast heartbeat, seizure and have a source of sugar at hand always. If you experience one of them or any unusual symptoms call your doctor immediately.
Storage
Precautions
Glucophage is an oral diabetes medicine used to treat type 2 of diabetes. Its active substance is Metformin which belongs to biguanide class of substances. It reduces concentration of glucose in blood suppressing metabolism of glucose in the liver, reducing absorption of glucose from the gastrointestinal tract, and enhancing its utilization in tissues. Glucophage stabilizes or reduces body weight. The therapeutic effect is not observed in the absence of insulin in the blood. It does not cause hypoglycemic reactions. It improves fibrinolytic properties of blood. It I used to treat diabetes mellitus (type 2) in adults also in patients for who treatment with sulfonylurea was ineffective, especially in cases followed by obesity.
Drug interaction
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
The following side effects are most common and be rather severe to stop taking of the medication: swelling or rapid weight gain, nausea, vomiting, gas, bloating, diarrhea and loss of appetite. In case of lactic acidosis also get emergency medical help: weakness, increasing drowsiness, slow heartbeat, cold feeling, shortness of breath, abdominal pain, muscle pain, lightheadedness, and fainting. Allergic reaction is also possible: hives, swelling, rash.
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