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Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.
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This medication should be taken after a meal with a big glass of water to decrease irritation of esophagus. Daily dose should be taken as a single dose or divided in two (12 hours between each one). Do not take it in larger amounts or continue to take it after the administered period. Certain brands of this medication cannot be used with dairy products. Do not crush, break, or open a delayed-release capsule, eat the pill whole. If it is an oral suspension shake it before use and measure with special measuring spoon. Never take this drug if it is expired as it may damage your kidney.
Co-administration with aluminum, magnesium, or calcium based antacids is not recommended as Doxycyline absorption maybe slowered. Minerals (such as calcium or iron) or with bismuth subsalicylate have the same effect. Doxycycline is reported to enhance the activity of warfarin. Phenytoin (Dilantin), carbamazepine (Tegretol), and barbiturates (such as phenobarbital) may enhance the metabolism of Doxycycline.
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