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Cimetidine and sodium bicarbonate reduce effects of Domperidone. Anticholinergic medications neutralize effect of Motilium. Blood levels of Motilium are increased by azole antifungal agents, macrolide antibiotics, HIV protease inhibitors, nefazodone (antidepressant). Motilium is compatible with antipsychotic (neuroleptics) medications, dopamine receptor agonists (bromocriptine, L-dopa). Simultaneous treatment with paracetamol and digoxin had no effect on the concentration of these medications in the blood.
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